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Furthermore, both SM and exenatide selectively activated p38 MAPK phosphorylation in the spinal cord, providing additional evidence that SM exerts its anti-allodynic effects by targeting spinal GLP-1R and promoting microglial β-endorphin synthesis via the p38 MAPK signaling cascade [72]
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Size and Gauge:31 Gauge, 0.3 mL, 5/16-inch
The authors also address ongoing challenges of accessibility and affordability, prompting important societal discussions about equitable distribution and funding for these lifechanging therapies
